Southampton continue to try and find their true winning form again after what has been a frustrating winter period so far.
The Saints have not gotten a solid result against Arsenal in nine previous meetings and they will hope that their home confines at St. Mary's will aid them in their pursuit of a much needed three points.
Both sides cruised through into the next round of the FA Cup over the weekend and will be in good spirits for what should be a great match.
Arsenal can go top of the table once again for at least 24 hours as Chelsea and Manchester City will be looking to take a shot at the top once more when they face off against West Ham and Tottenham tomorrow.
The Gunners have a nearly fully fit side and will go full force to hold onto their place at the top, but if they drop points then once again first place will be up for grabs.
Southampton XI: Boruc; Clyne, Hooiveld, Fonte, Shaw; Schneiderlin, Cork; Davis, Lallana, Rodriguez, Lambert.
Arsenal XI: Szczesny; Sagna, Mertesacker, Koscielny, Gibbs; Wilshere, Flamini; Gnabry, Ozil, Cazorla; Giroud.
