A car bomb targeted on Thursday the eastern region of Hermel, a Hezbollah stronghold, causing an unknown number of casualties.
The explosion ripped through Hermel's main square where the town's Serail lies.
A medic told Agence France Presse that three people were killed and 15 injured in the blast.
Earlier this month, a suicide car bombing shook the district of Haret Hreik in Beirut's southern suburbs.
That bombing was the fourth attack in Beirut's southern suburbs, a Hezbollah bastion, since the party announced it was fighting in Syria.
As well as the Iranian embassy suicide attacks in November, the southern suburbs also suffered an August 15 bombing and a blast earlier the same month.