It has already been a tough start to the week for Manchester United having suffered a humiliating defeat at home to their arch-rivals Liverpool.
David Moyes knows that his job is on the line whether he believes he is going anywhere or not in his press conferences.
The manager that has failed to produce the goods as expected is now fighting for his life and he cannot get some results in the next few matches he very well might be out the door this summer.
The Red Devils have to field an attacking side if they are to hope to overturn a two goal deficit that they incured in Greece.
Shinji Kagawa is expected to return to the first team according to comments from Moyes yesterday and with Juan Mata cup tied from Chelsea. Elsewhere the lineup should be close to what we saw against the Reds on Sunday.
Olympiakos have several injury and doubtful concerns but none the less will field their best team as they hope to find their way back to the promised land of European glory at the expense of a struggling English superpower.
United XI: De Gea: Rafael, Ferdinand, Vidic, Evra; Fallaini, Carrick; Valencia, Rooney, Kagawa; Persie.
Olympiakos XI: Roberto: Salino, Marcano, Manolas, Bong; Maniatis, Ndinga; Campbell, Dominguez, Fuster; Valdez.